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Development of a high-performance liquid chromatographic-electrospray mass spectrometric assay for the specific and sensitive quantification of the novel immunosuppressive macrolide 40-O-(2-hydroxyethyl)rapamycin

Author
SEGARRA, I1 ; BRAZELTON, T. R2 ; GUTERMAN, N1 ; HAUSEN, B2 ; JACOBSEN, W1 ; MORRIS, R. E2 ; BENET, L. Z1 ; CHRISTIANS, U1 2
[1] Department of Biopharmaceutical Sciences, University of California at San Francisco, San Francisco, CA 94143-0446, United States
[2] Laboratory of Transplantation Immunology, Department of Cardiothoracic Surgery, Stanford University Medical School, Stanford, CA 94305-5247, United States
Source

Journal of chromatography. B, Biomedical sciences and applications. 1998, Vol 720, Num 1-2, pp 179-187 ; ref : 20 ref

ISSN
1387-2273
Scientific domain
Biochemistry, molecular biology, biophysics; Medical laboratory techniques
Publisher
Elsevier Science, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Keyword (fr)
Analyse quantitative Chromatographie HPLC Détecteur UV Electrospray Etude comparative Homme Immunodépresseur Macrolide Sang Spectrométrie masse Transplantation Rapamycine dérivé Liquide biologique
Keyword (en)
Quantitative analysis HPLC chromatography Ultraviolet detector Electrospray Comparative study Human Immunosuppressive agent Macrolide Blood Mass spectrometry Transplantation Biological fluid
Keyword (es)
Análisis cuantitativo Cromatografía HPLC Detector UV Electrospray Estudio comparativo Hombre Inmunodepresor Macrólido Sangre Espectrometría masa Trasplantación Líquido biológico
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1655330

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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