Synthesis and biological activities of bisnaphthalimido polyamines derivatives: cytotoxicity, DNA binding, DNA damage and drug localization in breast cancer MCF 7 cells
- Author
- DANCE, Anne-Marie1 ; RALTON, Lynda1 ; FULLER, Zoe1 ; MILNE, Lesley2 ; DUTHIE, Susan2 ; BESTWICK, Charles S2 ; KONG THOO LIN, Paul1
[1] The Robert Gordon University, School of Life Sciences, St. Andrew Street, Aberdeen AB251HG, Scotland, United Kingdom
[2] The Rowett Research Institute, Greenburn Road, Aberdeen AB299SB, Scotland, United Kingdom - Source
Biochemical pharmacology. 2005, Vol 69, Num 1, pp 19-27, 9 p ; ref : 21 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier Science, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Bisnaphthalimides Cytotoxicity DNA binding and damage Fluorescence microscopy Single cell gel electrophoresis assay Synthesis
- Keyword (fr)
- Activité biologique Cellule tumorale Cytotoxicité Fixation biologique Glande mammaire pathologie Lésion Mécanisme action Polyamine Synthèse chimique Tumeur maligne Benzo[de]isoquinoléine-1,3-dione dérivé Cancer sein Lignée MCF7
- Keyword (en)
- Biological activity Tumor cell Cytotoxicity Biological fixation Mammary gland diseases Lesion Mechanism of action Polyamine Chemical synthesis Malignant tumor Breast cancer
- Keyword (es)
- Actividad biológica Célula tumoral Citotoxicidad Fijación biológica Glándula mamaria patología Lesión Mecanismo acción Poliamina Síntesis química Tumor maligno Cáncer del pecho
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16558833
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bcp.2004.09.020 
https://dx.doi.org/10.1016/j.bcp.2004.09.020
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