Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents
- Author
- ROUTIER, Sylvain; PEIXOTO, Paul; MEROUR, Jean-Yves; COUDERT, Gérard; DIAS, Nathalie; BAILLY, Christian; PIERRE, Alain1 ; LEONCE, Stéphane1 ; CAIGNARD, Daniel-Henry1
INSERM U-524, IRCL, Place de Verdun, 59045 Lille, France
Institut de Chimie Organique et Analytique, UMR CNRS 6005, Université d'orléans, Rue de Chartres, BP 6759, 45067 Orléans, France
[1] Institut de Recherches Servier, Division Recherche Cancérologie, 125 chemin de Ronde, 78290 Croissy sur Seine, France - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 5, pp 1401-1413, 13 p ; ref : 49 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cellule tumorale Composé aromatique Composé polycyclique Cytotoxicité Hétérocycle azote Imide In vitro Lignée L1210 Lignée cellulaire Relation structure activité Synthèse chimique Lignée DU145 Lignée HT29 Naphto[2,3-a]pyrrolo[3,4-c]carbazole dérivé Naphto[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione(6-[2-(diméthylamino)éthyl]-3-hydroxy) Naphtocarbazole Naphtopyrrolocarbazole
- Keyword (en)
- Antineoplastic agent Tumor cell Aromatic compound Polycyclic compound Cytotoxicity Nitrogen heterocycle Imide In vitro L1210 cell line Cell line Structure activity relation Chemical synthesis
- Keyword (es)
- Anticanceroso Célula tumoral Compuesto aromático Compuesto policíclico Citotoxicidad Heterociclo nitrógeno Imida In vitro Célula L1210 Línea celular Relación estructura actividad Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16599943
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm049213f 
https://dx.doi.org/10.1021/jm049213f
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