Novel ligands for the chemokine receptor-3 (CCR3) : A receptor-modeling study based on 5D-QSAR
- Author
- VEDANI, Angelo; DOBLER, Max; DOLLINGER, Horst1 ; HASSELBACH, Kai-Malte; BIRKE, Franz2 ; LILL, Markus A
Biographics Laboratory 3R, Friedensgasse 35, 4056 Basel, Switzerland
[1] Chemical Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach/Riss, Germany
[2] Pulmonary Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach/Riss, Germany - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 5, pp 1515-1527, 13 p ; ref : 53 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amine tertiaire Energie libre Ligand Modèle moléculaire Modélisation Pipérazine dérivé Propriété thermodynamique Prédiction Relation structure activité Récepteur chimiokine CCR3 Pipérazine(1-[1-aryl-2-(2-aryléthylamino)éthyl]-4-cyclohexyl) QSAR
- Keyword (en)
- Tertiary amine Free energy Ligand Molecular model Modeling Piperazine derivatives Thermodynamic properties Prediction Structure activity relation CCR3 chemokine receptor
- Keyword (es)
- Amina terciaria Energía libre Ligando Modelo molecular Modelización Piperazina derivado Propiedad termodinámica Predicción Relación estructura actividad Receptor quimioquina CCR3
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16599953
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm040827u 
https://dx.doi.org/10.1021/jm040827u
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