Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists
- Author
- CAPPELLACCI, Loredana; FRANCHETTI, Palmarisa; GRIFANTINI, Mario; PASQUALINI, Michela; PETRELLI, Riccardo; VITA, Patrizia; LAVECCHIA, Antonio; NOVELLINO, Ettore; COSTA, Barbara; MARTINI, Claudia; KLOTZ, Karl-Norbert1
Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, 80131 Napoli, Italy
Dipartimento di Neurobiologia, Farmacologia e Biotecnologia, Università di Pisa, 56126 Pisa, Italy
Dipartimento di Scienze Chimiche, Università di Camerino, 62032 Camerino, Italy
[1] Institut fur Pharmakologie und Toxikologie, Universität Würzburg, 97078 Würzburg, Germany - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 5, pp 1550-1562, 13 p ; ref : 42 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acide uronique Agoniste Animal Bovin Carboxamide Composé ramifié In vitro Modèle moléculaire Modélisation Purine nucléoside Relation structure activité Récepteur adénosinique Synthèse chimique Adénine(9-[N-éthyl-3-méthyl-β-D-ribofuranosyluronamide]) Adénosine dérivé Adénosine(N6-cyclohexyl-2p-méthyl) Adénosine-5p-carboxamide dérivé Artiodactyla Mammalia Ungulata Vertebrata
- Keyword (en)
- Uronic acid Agonist Animal Bovine Carboxamide Branched compound In vitro Molecular model Modeling Purine nucleoside Structure activity relation Adenosine receptor Chemical synthesis Artiodactyla Mammalia Ungulata Vertebrata
- Keyword (es)
- Acido urónico Agonista Animal Bovino Carboxamida Compuesto ramificado In vitro Modelo molecular Modelización Purina nucleósido Relación estructura actividad Receptor adenosínico Síntesis química Artiodactyla Mammalia Ungulata Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09F Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16599956
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm049408n 
https://dx.doi.org/10.1021/jm049408n
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