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Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors

Author
DASGUPTA, Biplab1 ; YIJUN YI1 ; CHEN, David Y2 ; WEBER, Jason D2 ; GUTMANN, David H1
[1] Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States
[2] Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States
Source

Cancer research (Baltimore). 2005, Vol 65, Num 7, pp 2755-2760, 6 p ; ref : 43 ref

CODEN
CNREA8
ISSN
0008-5472
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
American Association for Cancer Research, Philadelphia, PA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Animal Ciblage Cible Homme Intracrânien Mammalia Neurofibromatose Recklinghausen Protéome Sirolimus Souris Transduction signal Tumeur intracrânienne Lactone Macrocycle Macrolide Maladie héréditaire Peau pathologie Phacomatose Rodentia Système nerveux pathologie Tumeur bénigne Vertebrata
Keyword (en)
Animal Targeting Target Human Intracranial Mammalia Neurofibromatosis Recklinghausen Proteome Sirolimus Mouse Signal transduction Intracranial tumor Lactone Macrocycle Macrolide Genetic disease Skin disease Phacomatosis Rodentia Nervous system diseases Benign neoplasm Vertebrata
Keyword (es)
Animal Blancado Blanco Hombre Intracraneal Mammalia Neurofibromatosis Recklinghausen Proteoma Sirolimús Ratón Transducción señal Tumor intracraneal Lactona Macrociclo Macrólido Enfermedad hereditaria Piel patología Facomatosis Rodentia Sistema nervioso patología Tumor benigno Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses

Discipline
Neurology Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16634371

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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