Nitrile biotransformations for highly enantioselective synthesis of oxiranecarboxamides with tertiary and quaternary stereocenters : Efficient chemoenzymatic approaches to enantiopure α-methylated serine and isoserine derivatives
- Author
- WANG, Mei-Xiang1 ; GANG DENG1 ; WANG, De-Xian1 ; ZHENG, Qi-Yu1
[1] Laboratory for Chemical Biology, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China - Source
Journal of organic chemistry. 2005, Vol 70, Num 7, pp 2439-2444, 6 p ; ref : 26 ref
- CODEN
- JOCEAH
- ISSN
- 0022-3263
- Scientific domain
- Biochemistry, molecular biology, biophysics; Organic chemistry
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amidase Amine Aminoacide Benzènepropionique acide Biotransformation Carboxamide Composé chiral Condition opératoire modérée Décyclisation Enantiosélectivité Epoxyde Excès énantiomère Hétérocycle oxygène Méthode enzymatique Nitrile hydratase Nitrile Oxirane dérivé Rhodococcus Régiosélectivité Stéréospécificité Synthèse chimique Sérine Isosérine Actinomycetes Bactérie Carbon-oxygen lyases Enzyme Hydro-lyases Hydrolases Lyases
- Keyword (en)
- Amidase Amine Aminoacid Benzenepropionic acid Biotransformation Carboxamide Chiral compound Mild operating conditions Ring cleavage Enantioselectivity Epoxide Enantiomeric excess Oxygen heterocycle Enzymatic method Nitrile hydratase Nitrile Oxirane derivatives Rhodococcus Regioselectivity Stereospecificity Chemical synthesis Serine Actinomycetes Bacteria Carbon-oxygen lyases Enzyme Hydro-lyases Hydrolases Lyases
- Keyword (es)
- Amidase Amina Aminoácido Bencenopropionico ácido Biotransformación Carboxamida Compuesto quiral Condición operatoria moderada Desciclización Enantioselectividad Epóxido Exceso enantiómero Heterociclo oxígeno Método enzimático Nitrile hydratase Nitrilo Oxirano derivado Rhodococcus Regioselectividad Estereoespecificidad Síntesis química Serina Actinomycetes Bacteria Carbon-oxygen lyases Enzima Hydro-lyases Hydrolases Lyases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31C Methods. Procedures. Technologies / 002A31C06 Bioconversions. Hemisynthesis
- Discipline
- Biotechnology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16639735
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jo0482615 
https://dx.doi.org/10.1021/jo0482615
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