Structure based activity prediction of HIV-1 reverse transcriptase inhibitors
- Author
- DE JONGE, Marc R1 ; KOYMANS, Lucien M. H1 ; VINKERS, H. Maarten1 ; DAEYAERT, Frits F. D1 ; HEERES, Jan1 ; LEWI, Paul J1 ; JANSSENA, Paul A. J1
[1] Center for Molecular Design, Johnson & Johnson Pharmaceutical Research and Development, Janssen Pharmaceutica NV, Antwerpsesteenweg 37, 2350 Vosselaar, Belgium - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 6, pp 2176-2183, 8 p ; ref : 24 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiviral Complexe enzyme inhibiteur Inhibiteur enzyme Inhibiteur reverse transcriptase Modèle moléculaire Modélisation Prédiction RNA-directed DNA polymerase Relation structure activité Site actif Virus HIV1 Enzyme Lentivirus Nucleotidyltransferases Retroviridae Transferases Virus immunodéficience humaine Virus
- Keyword (en)
- Antiviral Inhibitor enzyme complex Enzyme inhibitor Reverse transcriptase inhibitor Molecular model Modeling Prediction RNA-directed DNA polymerase Structure activity relation Active site HIV-1 virus Enzyme Lentivirus Nucleotidyltransferases Retroviridae Transferases Human immunodeficiency virus Virus
- Keyword (es)
- Antiviral Complejo enzima inhibidor Inhibidor enzima Inhibitor reverse transcriptase Modelo molecular Modelización Predicción RNA-directed DNA polymerase Relación estructura actividad Lugar activo HIV-1 virus Enzima Lentivirus Nucleotidyltransferases Retroviridae Transferases Human immunodeficiency virus Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16655420
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm049534r 
https://dx.doi.org/10.1021/jm049534r
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