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Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018)

Author
HAN, Xiang-Yu1 ; HE LIU1 ; LIU, Chun-He1 ; BO WU1 ; CHEN, Lan-Fu1 ; ZHONG, Bo-Hua1 ; LIU, Ke-Liang1
[1] No. 7 Department, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China
Source

Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 8, pp 1979-1982, 4 p

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Asymmetric Epoxidation Isomers Penehyclidine hydrochloride
Keyword (fr)
Antagoniste Chlorhydrate Diastéréoisomère Diastéréosélectivité Epoxydation Hydroxyéther Quinuclidine dérivé Récepteur cholinergique Sulfonate Synthèse chimique Quinuclidine(3-[β-cyclopentyl-β-hydroxyphénéthyloxy])
Keyword (en)
Antagonist Hydrochlorides Diastereomer Diastereoselectivity Epoxidation Hydroxyether Quinuclidine derivatives Cholinergic receptor Sulfonate Chemical synthesis
Keyword (es)
Antagonista Hidrocloruro Diasteréomero Diastereoselectividad Epoxidación Hidroxieter Receptor colinérgico Sulfonato Síntesis química
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06B Heterocyclic compounds with only one n hetero atom and condensed derivatives

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09B Cholinergic system

Discipline
Organic chemistry Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16678891

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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