Synthesis and antitumor activity of 7-ethyl-9-alkyl derivatives of camptothecin
- Author
- HEYONG GAO1 ; XIONGWEN ZHANG1 ; YI CHEN1 ; HONGWU SHEN1 ; JING SUN1 ; MIN HUANG1 ; JIAN DING1 ; CHUAN LI1 ; WEI LU1
[1] Shanghai Institute of Materia Medico, SIBS, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang High-Tech Park, Shanghai 201203, China - Source
Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 8, pp 2003-2006, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Antitumor activity Camptothecin Topoisomerase I
- Keyword (fr)
- Activité biologique Alcaloïde Animal Anticancéreux Cellule tumorale Cytotoxicité Côlon DNA topoisomerase Homme In vitro Inhibiteur enzyme Lactame Lactone Lignée cellulaire Plasma sanguin Sarcome 180 Souris Stabilité Synthèse chimique Transposition Claisen Tumeur solide Camptothécine(10-allyl-11-éthyl-9-hydroxy) Lignée Bel7402 Lignée HCT116 Enzyme Isomerases Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Alkaloid Animal Antineoplastic agent Tumor cell Cytotoxicity Colon DNA topoisomerase Human In vitro Enzyme inhibitor Lactam Lactone Cell line Blood plasma Sarcoma 180 Mouse Stability Chemical synthesis Claisen rearrangement Solid tumor Enzyme Isomerases Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Alcaloide Animal Anticanceroso Célula tumoral Citotoxicidad Colón DNA topoisomerase Hombre In vitro Inhibidor enzima Lactamo Lactona Línea celular Plasma sanguíneo Sarcoma 180 Ratón Estabilidad Síntesis química Transposición Claisen Tumor sólido Enzima Isomerases Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16678896
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2005.02.072 
https://dx.doi.org/10.1016/j.bmcl.2005.02.072
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