Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells
- Author
- WANG, H1 ; IEZZI, M1 ; THEANDER, S1 ; ANTINOZZI, P. A1 ; GAUTHIER, B. R1 ; HALBAN, P. A2 ; WOLLHEIM, C. B1
[1] Department of Cell Physiology and Metabolism, University Medical Center, 1211 Geneva, Switzerland
[2] Department of Medical Genetics and Development, University Medical Center, Geneva, Switzerland - Source
Diabetologia (Berlin). 2005, Vol 48, Num 4, pp 720-731, 12 p ; ref : 71 ref
- ISSN
- 0012-186X
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Beta cell CAMP FGFR1 GLP-1 receptor IPF-1 MODY4 Pdx-1 Prohormone convertase-1
- Keyword (fr)
- AMP cyclique Cellule β Diabète Insuline Prohormone Proinsuline Récepteur biologique Suppression Sécrétion Endocrinopathie Hormone pancréatique Ilot Langerhans Pancréas endocrine
- Keyword (en)
- Cyclic AMP β Cell Diabetes mellitus Insulin Prohormone Proinsulin Biological receptor Suppression Secretion Endocrinopathy Pancreatic hormone Langerhans islet Endocrine pancreas
- Keyword (es)
- AMP cíclico Célula β Diabetes Insulina Prohormona Proinsulina Receptor biológico Supresión Secreción Endocrinopatía Hormona pancreática Isla Langerhans Páncreas endocrino
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Discipline
- Endocrinopathies
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16695104
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00125-005-1692-8 
https://dx.doi.org/10.1007/s00125-005-1692-8
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