Synthesis, pharmacological activity and hydrolytic behavior of glyceride prodrugs of ibuprofen
- Author
- KHAN, M. S. Y1 ; AKHTER, Mymoona1
[1] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India - Source
European journal of medicinal chemistry. 2005, Vol 40, Num 4, pp 371-376, 6 p ; ref : 16 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- : NSAIDs Glyceride prodrugs Ibuprofen Pharmacokinetics
- Keyword (fr)
- Animal Antiinflammatoire non stéroïde Biodisponibilité Chimiothérapie Cinétique Diacylglycérol Estomac Glycéride Hydrolyse Ibuprofène In vitro In vivo Lipide Pharmacocinétique Promédicament Rat Relation structure activité Solution tampon Synthèse chimique Toxicité Traitement Ulcère Voie orale Appareil digestif pathologie Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Non steroidal antiinflammatory agent Bioavailability Chemotherapy Kinetics Diacylglycerol Stomach Glyceride Hydrolysis Ibuprofen In vitro In vivo Lipids Pharmacokinetics Prodrug Rat Structure activity relation Buffer solution Chemical synthesis Toxicity Treatment Ulcer Oral administration Digestive diseases Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Antiinflamatorio no esteroide Biodisponibilidad Quimioterapia Cinética Diacilglicerol Estómago Glicérido Hidrólisis Ibuprofeno In vitro In vivo Lípido Farmacocinética Promedicamento Rata Relación estructura actividad Solución de amortiguación Síntesis química Toxicidad Tratamiento Ulcera Vía oral Aparato digestivo patología Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16706136
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2004.11.009 
https://dx.doi.org/10.1016/j.ejmech.2004.11.009
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