Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal
- Author
- RISBUD, Makarand V1 ; FERTALA, Jolanta1 ; VRESILOVIC, Edward J2 ; ALBERT, Todd J1 ; SHAPIRO, Irving M1
[1] Division of Orthopaedic Research, Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA, United States
[2] Department of Biomedical Engineering, Drexel University, Philadelphia, PA, United States - Source
Spine (Philadelphia, PA. 1976). 2005, Vol 30, Num 8, pp 882-889, 8 p ; ref : 29 ref
- CODEN
- SPINDD
- ISSN
- 0362-2436
- Scientific domain
- Neurology; Orthopedics traumatology
- Publisher
- Lippincott, Hagerstown, MD
/
Lippincott, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Akt MAPK aggrecan apoptosis hypoxia nucleus pulposus serum
- Keyword (fr)
- Apoptose Canal rachidien Extracellular signal-regulated protein kinase Hypoxie Mitogen-activated protein kinase Moelle épinière pathologie Nucléus pulposus Système nerveux pathologie Transduction signal Enzyme Oxygène Système nerveux central pathologie
- Keyword (en)
- Apoptosis Vertebral canal Extracellular signal-regulated protein kinase Hypoxia Mitogen-activated protein kinase Spinal cord disease Nucleus pulposus Nervous system diseases Signal transduction Enzyme Oxygen Central nervous system disease
- Keyword (es)
- Apoptosis Canal vertebral Extracellular signal-regulated protein kinase Hipoxia Mitogen-activated protein kinase Médula espinal patología Núcleo pulposo Sistema nervioso patología Transducción señal Enzima Oxígeno Sistema nervosio central patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25L Development. Senescence. Regeneration. Transplantation
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U01 Toxicity: nervous system and muscle
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A07 Cerebrospinal fluid. Meninges. Spinal cord
- Discipline
- Drugs toxicity and drug intoxications Neurology Toxicology Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16711103
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1097/01.brs.0000159096.11248.6d 
https://dx.doi.org/10.1097/01.brs.0000159096.11248.6d
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