Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity
- Author
- KVASNICA, Miroslav1 ; SAREK, Jan1 ; KLINOTOVA, Eva1 ; DZUBAK, Petr2 ; HAJDUCH, Marian2
[1] Department of Organic and Nuclear Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, 128 43 Prague, Czech Republic
[2] Laboratory of Experimental Medicine, Departments of Pediatrics and Oncology, Faculty of Medicine, Palacky University in Olomouc, Puskinova 6, 775 20 Olomouc, Czech Republic - Source
Bioorganic & medicinal chemistry. 2005, Vol 13, Num 10, pp 3447-3454, 8 p ; ref : 15 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Betulin Cytotoxicity Phthalate Triterpenes
- Keyword (fr)
- Acylate Alcool secondaire Anticancéreux Cellule tumorale Composé benzénique Composé pentacyclique Composé saturé Cytotoxicité Ester In vitro Lignée cellulaire Phtalate Polluant Relation structure activité Synthèse chimique Terpénoïde Triterpène Bétuline dérivé Bétulinique acide dérivé Lupane dérivé Phtalique acide dérivé
- Keyword (en)
- Acylate Secondary alcohol Antineoplastic agent Tumor cell Benzenic compound Pentacyclic compound Saturated compound Cytotoxicity Ester In vitro Cell line Phthalates Pollutant Structure activity relation Chemical synthesis Terpenoid Triterpene
- Keyword (es)
- Acilato Alcohol secundario Anticanceroso Célula tumoral Compuesto bencénico Compuesto pentacíclico Compuesto saturado Citotoxicidad Ester In vitro Línea celular Contaminante Relación estructura actividad Síntesis química Terpenoide Triterpeno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16742156
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2005.03.006 
https://dx.doi.org/10.1016/j.bmc.2005.03.006
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