Synthesis and biological evaluation of gemcitabine-lipid conjugate (NEO6002)
- Author
- ALI, Shoukath M1 ; KHAN, Abdul R1 ; AHMAD, Moghis U1 ; CHEN, Paul1 ; SHEIKH, Saifuddin1 ; AHMAD, Imran1
[1] NeoPharm Inc., Research and Development Facility, 1850 Lakeside Drive, Waukegan, IL 60085, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 10, pp 2571-2574, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Cardiolipin Gemcitabine Lipid-nucleoside conjugate Prodrug
- Keyword (fr)
- Activité biologique Animal Anticancéreux Cellule tumorale Composé conjugué Diphosphatidylglycérol Fluor Composé organique Gemcitabine Homme In vivo Lignée cellulaire Pancréas Pathologie expérimentale Phospholipide Promédicament Pyrimidine nucléoside Souris Synthèse chimique Toxicité Tumeur Lignée BxPC3 Lipide complexe Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Antineoplastic agent Tumor cell Conjugated compound Diphosphatidylglycerol Fluorine Organic compounds Gemcitabine Human In vivo Cell line Pancreas Experimental disease Phospholipid Prodrug Pyrimidine nucleoside Mouse Chemical synthesis Toxicity Tumor Complex lipid Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Anticanceroso Célula tumoral Compuesto conjugado Difosfatidilglicerol Fluor Compuesto orgánico Gemcitabina Hombre In vivo Línea celular Páncreas Patología experimental Fosfolípido Promedicamento Pirimidina nucleósido Ratón Síntesis química Toxicidad Tumor Lípido complejo Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16746167
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2005.03.046 
https://dx.doi.org/10.1016/j.bmcl.2005.03.046
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