On the binding of indeno[1,2-c]isoquinolines in the DNA-topoisomerase I cleavage complex
- Author
- XIANGSHU XIAO1 ; ANTONY, Smitha2 ; POMMIER, Yves2 ; CUSHMAN, Mark1
[1] Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, Indiana 47907, United States
[2] Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-4255, United States - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 9, pp 3231-3238, 8 p ; ref : 40 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agent intercalant Anticancéreux Clivage DNA topoisomerase Fixation biologique Interaction moléculaire Modèle moléculaire Modélisation Prédiction Relation structure activité Indéno[1,2-c]isoquinoléine dérivé Indénoisoquinoléine Enzyme Isomerases
- Keyword (en)
- Intercalating agent Antineoplastic agent Cleavage DNA topoisomerase Biological fixation Molecular interaction Molecular model Modeling Prediction Structure activity relation Enzyme Isomerases
- Keyword (es)
- Agente intercalante Anticanceroso Clivaje DNA topoisomerase Fijación biológica Interacción molecular Modelo molecular Modelización Predicción Relación estructura actividad Enzima Isomerases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16758000
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm050017y 
https://dx.doi.org/10.1021/jm050017y
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