Structure-activity relationships of fluorinated lysophosphatidic acid analogues
- Author
- YONG XU1 ; AOKI, Junken2 ; PRESTWICH, Glenn D1 ; SHIMIZU, Kumiko2 ; UMEZU-GOTO, Makiko2 ; HAMA, Kotaro2 ; TAKANEZAWA, Yasukazu2 ; SHUANGXING YU3 ; MILLS, Gordon B3 ; ARAI, Hiroyuki2 ; LIAN QIAN1
[1] Department of Medicinal Chemistry and The Center for Cell Signaling, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, Utah 84108-1257, United States
[2] Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan
[3] Department of Molecular Therapeutics, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, United States - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 9, pp 3319-3327, 9 p ; ref : 32 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agoniste Cellule tumorale Côlon Fluor Composé organique Homme In vitro Lignée cellulaire Lysophosphatidique acide Lysophospholipide Ovaire Phospholipide Phosphonique acide Phosphore Composé organique Protein kinase Relation structure activité Récepteur lysophospholipide edg7 Synthèse chimique Transduction signal Lignée HT29 Lignée OVCAR3 Lignée SKOV3 Stéarique acide ester 4-[dihydroxyphosphoryl]-4-fluoro-2-hydroxybutyle Enzyme Lipide complexe Transferases
- Keyword (en)
- Agonist Tumor cell Colon Fluorine Organic compounds Human In vitro Cell line Lysophosphatidic acid Lysophospholipid Ovary Phospholipid Phosphonic acids Phosphorus Organic compounds Protein kinase Structure activity relation edg7 lysophospholipid receptor Chemical synthesis Signal transduction Enzyme Complex lipid Transferases
- Keyword (es)
- Agonista Célula tumoral Colón Fluor Compuesto orgánico Hombre In vitro Línea celular Lisofosfatídico ácido Lisofosfolípido Ovario Fosfolípido Fósforo Compuesto orgánico Protein kinase Relación estructura actividad Receptor lisofosfolípido edg7 Síntesis química Transducción señal Enzima Lípido complejo Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16758008
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm049186t 
https://dx.doi.org/10.1021/jm049186t
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