Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4
- Author
- HAZELDINE, Stuart T1 ; POLIN, Lisa1 ; KUSHNER, Juiwanna1 ; WHITE, Kathryn1 ; CORBETT, Thomas H1 ; HORWITZ, Jerome P1
[1] Department of Internal Medicine, Division of Hematology and Oncology, Wayne State University School of Medicine, Barbara Ann Karmanos Cancer Institute, Detroit, MI, United States - Source
Bioorganic & medicinal chemistry. 2005, Vol 13, Num 12, pp 3910-3920, 11 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Analogs Antitumor SH80 XK469
- Keyword (fr)
- Acide carboxylique Animal Anticancéreux Cellule tumorale Chimiothérapie Composé aromatique Composé bicyclique Composé monocyclique Cyclopropane dérivé Cytotoxicité Ester Ether Hétérocycle azote In vitro In vivo Lignée cellulaire Propionique acide dérivé Quinoxaline dérivé Relation structure activité Souris Synthèse chimique Traitement Tumeur solide Voie intraveineuse Voie orale Cyclopropanecarboxylique acide dérivé Chlore Composé organique Fluor Composé organique Mammalia Rodentia Tumeur maligne Vertebrata
- Keyword (en)
- Carboxylic acid Animal Antineoplastic agent Tumor cell Chemotherapy Aromatic compound Bicyclic compound Monocyclic compound Cyclopropane derivatives Cytotoxicity Ester Ether Nitrogen heterocycle In vitro In vivo Cell line Propionic acid derivatives Quinoxaline derivatives Structure activity relation Mouse Chemical synthesis Treatment Solid tumor Intravenous administration Oral administration Chlorine Organic compounds Fluorine Organic compounds Mammalia Rodentia Malignant tumor Vertebrata
- Keyword (es)
- Acido carboxílico Animal Anticanceroso Célula tumoral Quimioterapia Compuesto aromático Compuesto bicíclico Compuesto monocíclico Ciclopropano derivado Citotoxicidad Ester Eter Heterociclo nitrógeno In vitro In vivo Línea celular Propionico ácido derivado Quinoxalina derivado Relación estructura actividad Ratón Síntesis química Tratamiento Tumor sólido Vía intravenosa Vía oral Cloro Compuesto orgánico Fluor Compuesto orgánico Mammalia Rodentia Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16800562
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2005.04.011 
https://dx.doi.org/10.1016/j.bmc.2005.04.011
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