Non-competitive inhibitors of metabotropic glutamate receptor 5 (mGluR5)
- Author
- TASLER, Stefan; KRAUS, Jürgen; PEGORARO, Stefano; ASCHENBRENNER, Andrea; POGGESI, Elena2 ; TESTA, Rodolfo2 ; MOTTA, Gianni2 ; LEONARDI, Amedeo2
[2] Rccordati Industria Chimica E Furmaceutica S. p. A., Via Matteo Civitali 1, 20148 Milan, Italy - Source
Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 11, pp 2876-2880, 5 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Metabotropic glutamate receptor Molecular modeling Neuroplasticity Non-competitive antagonist
- Keyword (fr)
- Affinité Antagoniste Benzoïque acide dérivé Benzène dérivé Composé bicyclique Composé tricyclique Cycle 5 chaînons Cycle 6 chaînons Cétone Ester Homme Hétérocycle azote Hétérocycle oxygène azote Imide In vitro Inhibition compétitive Modèle moléculaire Modélisation Récepteur glutamate mglu groupe I Récepteur glutamate mglu5 Récepteur glutamate Récepteur métabotropique Sélectivité
- Keyword (en)
- Affinity Antagonist Benzoic acid derivatives Benzene derivatives Bicyclic compound Tricyclic compound Five membered ring Six membered ring Ketone Ester Human Nitrogen heterocycle Oxygen nitrogen heterocycle Imide In vitro Competitive inhibition Molecular model Modeling Group I mglu glutamate receptor mglu5 glutamate receptor Glutamate receptor Metabotropic receptor Selectivity
- Keyword (es)
- Afinidad Antagonista Benzoico ácido derivado Benceno derivado Compuesto bicíclico Compuesto tricíclico Ciclo 5 eslabones Ciclo 6 eslabones Cetona Ester Hombre Heterociclo nitrógeno Heterociclo oxígeno nitrógeno Imida In vitro Inhibición competitiva Modelo molecular Modelización Réceptor glutamato grupo I Receptor glutamato mglu5 Receptor glutámato Receptor metabotropico Selectividad
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09E Glutamatergic system (aspartate and other excitatory aminoacids)
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16810678
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2005.03.089 
https://dx.doi.org/10.1016/j.bmcl.2005.03.089
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