Synthesis and monoamine transporter binding properties of 3α-(substituted phenyl)nortropane-2β-carboxylic acid methyl esters. Norepinephrine transporter selective compounds
- Author
- CARROLL, F. Ivy1 ; TYAGI, Sameer1 ; BLOUGH, Bruce E1 ; KUHAR, Michael J2 ; NAVARRO, Hernn A1
[1] Chemistry and Life Sciences, Research Triangle Institute, Research Triangle Park, North Carolina 27709, United States
[2] Yerkes National Primate Center of Emory University, 954 Gatewood Road NE, Atlanta, Georgia 30329, United States - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 11, pp 3852-3857, 6 p ; ref : 18 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Affinité Amine biogène Benzène dérivé Catécholamine Composé bicyclique Fixation biologique Hétérocycle azote In vitro Ligand Neurotransmetteur Noradrénaline Protéine transport Relation structure activité Synthèse chimique Sélectivité Transport biologique Transport membranaire 8-Azabicyclo[3.2.1]octane dérivé Nortropane-2β-carboxylique acide(3α-[3-fluoro-4-méthylphényl]) ester méthye Transporteur monoamine Fluor Composé organique
- Keyword (en)
- Affinity Biogenic amine Benzene derivatives Catecholamine Bicyclic compound Biological fixation Nitrogen heterocycle In vitro Ligand Neurotransmitter Norepinephrine Carrier protein Structure activity relation Chemical synthesis Selectivity Biological transport Membrane transport Fluorine Organic compounds
- Keyword (es)
- Afinidad Amina biógena Benceno derivado Catecolamina Compuesto bicíclico Fijación biológica Heterociclo nitrógeno In vitro Ligando Neurotransmisor Noradrenalina Proteína transportador Relación estructura actividad Síntesis química Selectividad Transporte biológico Transporte membranal Fluor Compuesto orgánico
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09A Catecholaminergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16812149
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm058164j 
https://dx.doi.org/10.1021/jm058164j
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