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Synergistic effect of SU11248 with cytarabine or daunombicin on FLT3 ITD-positive leukemic cells

Author
YEE, Kevin W. H; SCHITTENHELM, Marcus; O'FARRELL, Anne-Marie; TOWN, Ajia R; MCGREEVEY, Laura; BAINBRIDGE, Troy; CHERRINGTON, Julie M; HEINRICH, Michael C
Clinic for Internal Medicine, Department of Hematology, Oncology, Immunology and Rheumatology, University of Tuebingen, Tuebingen, Germany
Oregon Health and Science University Cancer Institute and Portland Veterans Affairs Medical Center, Portland, OR, United States
Preclinical Research and Exploratory Development, SUGEN, South San Francisco, CA, United States
Source

Blood. 2004, Vol 104, Num 13, pp 4202-4209, 8 p ; ref : 51 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Aigu Anticancéreux Association médicamenteuse Cytarabine Daunorubicine Homme In vitro Inhibiteur Leucémie myéloblastique Lignée cellulaire établie Synergie Récepteur tyrosine kinase FLT3 SU 11248 Antimétabolite Hémopathie maligne Pyrimidine nucléoside
Keyword (en)
Biological activity Acute Antineoplastic agent Drug combination Cytarabine Daunorubicin Human In vitro Inhibitor Acute myelocytic leukemia Established cell line Synergism Fms-like tyrosine kinase 3 Antimetabolic Malignant hemopathy Pyrimidine nucleoside
Keyword (es)
Actividad biológica Agudo Anticanceroso Asociación medicamentosa Citarabina Daunorubicina Hombre In vitro Inhibidor Leucemia mieloblástica Línea celular establecida Sinergia Antimetabólito Hemopatía maligna Pirimidina nucleósido
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16835011

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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