New medium oxacyclic O,N-acetals and related open analogues : Biological activities
- Author
- CAMPUS, Joaquin1 ; SANIGER, Estrella1 ; MARCHAL, Juan A2 ; AIELLO, Stefania1 ; SUAREZ, Inés3 ; BOULAIZ, Houria3 ; ARANEGA, Antonia3 ; GALLO, Miguel A1 ; ESPINOSA, Antonio1
[1] Departamento de Química Farmacéutica y Orgánica, Facultad de Farmacla, c/ Campus de Cartuja s/n, 18071 Granada, Spain
[2] Departamento de Ciencias de la Salud, Facultad de Ciencias Experimentales y de la Salud, Paraje de las Lagunillas s/n, 23071 Jaén, Spain
[3] Departamento de Anatomía y Embriología Humana, Facultad de Medicina, Avenida de Madrid s/n, 18071 Granada, Spain - Source
Current medicinal chemistry. 2005, Vol 12, Num 12, pp 1423-1438, 16 p ; ref : 80 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham Science, Schiphol
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- 1-[3-(hydroxymethyl)-1,4-dioxepan-5yl]pyrimidines Anti-tumour drugs benzodioxepins breast cancer cell cycle lipophilicity neighbouring group participation programmed cell death
- Keyword (fr)
- Acétal Anticancéreux Apoptose Article synthèse Cellule tumorale Cycle cellulaire Fluorouracil Glande mammaire pathologie Glande mammaire Homme Lignée cellulaire Lipophilie Marqueur biologique Mort cellulaire Mécanisme action Médicament Pyrimidine dérivé Relation structure activité Tégafur 1,4-Dioxépane dérivé Benzodioxépine dérivé Lignée MCF7 Antimétabolite Fluoropyrimidine dérivé
- Keyword (en)
- Acetal Antineoplastic agent Apoptosis Review Tumor cell Cell cycle Fluorouracil Mammary gland diseases Mammary gland Human Cell line Lipophilicity Biological marker Cell death Mechanism of action Drug Pyrimidine derivatives Structure activity relation Tegafur Antimetabolic Fluoropyrimidine derivatives
- Keyword (es)
- Acetal Anticanceroso Apoptosis Artículo síntesis Célula tumoral Ciclo celular Fluorouracilo Glándula mamaria patología Glándula mamaria Hombre Línea celular Lipofilia Marcador biológico Muerte celular Mecanismo acción Medicamento Pirimidina derivado Relación estructura actividad Tegafur Antimetabólito Fluoropirimidina derivado
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16845133
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/0929867054020927 
https://dx.doi.org/10.2174/0929867054020927
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