Preparation of celecoxib-dimethyl-β-cyclodextrin inclusion complex : characterization and in vitro permeation study
- Author
- VENTURA, Cinzia Anna1 ; GIANNONE, Ignazio2 ; PAOLINO, Donatella3 ; PISTARA, Venerando4 ; CORSARO, Antonino4 ; PUGLISI, Giovanni2
[1] Pharmaco-Chemical Department, Faculty of Pharmacy, University of Messina, V. le Annunyata, 98168 Messina, Italy
[2] Department of Pharmaceutical Sciences, University of Catania, V. le A. Doria, 6, 95125 Catania, Italy
[3] Pharmacobiological Department, University of Calamaro Magna Grceda, 88021 Catanzaro, Italy
[4] Department of Chemical Sciences, University of Catania, V. le A. Doria, 6, 95125 Catania, Italy - Source
European journal of medicinal chemistry. 2005, Vol 40, Num 7, pp 624-631, 8 p ; ref : 22 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- 2,6-di-O-Methyl-β-cyclodextrin Celecoxib Chemical-physical characterization Permeation through CaCo-2 cells
- Keyword (fr)
- Antiinflammatoire non stéroïde Composé inclusion Constante stabilité Cyclodextrine Cyclooxygenase 2 Célécoxib Côlon Etat solide Homme In vitro Inhibiteur enzyme Lignée cellulaire Perméation Pharmacocinétique Propriété thermodynamique Pyrazole dérivé Solution aqueuse Sulfonamide Cycloheptaamylose(heptakis[2,6-di-O-méthyl]) Lignée CACO2 Enzyme Oxidoreductases
- Keyword (en)
- Non steroidal antiinflammatory agent Inclusion compound Stability constant Cyclodextrin Cyclooxygenase 2 Celecoxib Colon Solid state Human In vitro Enzyme inhibitor Cell line Permeation Pharmacokinetics Thermodynamic properties Pyrazole derivatives Aqueous solution Sulfonamide Enzyme Oxidoreductases
- Keyword (es)
- Antiinflamatorio no esteroide Compuesto inclusión Constante estabilidad Ciclodextrina Cyclooxygenase 2 Celecoxib Colón Estado sólido Hombre In vitro Inhibidor enzima Línea celular Permeación Farmacocinética Propiedad termodinámica Pirazol derivado Solución acuosa Sulfonamida Enzima Oxidoreductases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16855411
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2005.03.001 
https://dx.doi.org/10.1016/j.ejmech.2005.03.001
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