Synthesis and identification of small molecules that potently induce apoptosis in melanoma cells through G1 cell cycle arrest
- Author
- DOTHAGER, Robin S1 ; PUTT, Karson S1 ; ALLEN, Brittany J2 ; LESLIE, Benjamin J2 ; NESTERENKO, Vitaliy2 ; HERGENROTHER, Paul J1 2
[1] Department of Chemistry, Roger Adams Laboratory, University of Illinois, Urbana, Illinois 61801, United States
[2] Department of Biochemistry, Roger Adams Laboratory, University of Illinois, Urbana, Illinois 61801, United States - Source
Journal of the American Chemical Society. 2005, Vol 127, Num 24, pp 8686-8696, 11 p ; ref : 49 ref
- CODEN
- JACSAT
- ISSN
- 0002-7863
- Scientific domain
- Biochemistry, molecular biology, biophysics; Chemistry; Organic chemistry; Atomic molecular physics
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Amide organique Apoptose Cancérologie Cellule tumorale Mélanome malin Phase G1 Relation structure activité Relation structure fonction Relation structure propriété Acétique acide(triphényl) arylamide Propionique acide(triphényl) arylamide
- Keyword (en)
- Biological activity Organic amide Apoptosis Cancerology Tumor cell Malignant melanoma G1 Phase Structure activity relation Structure function relationship Property structure relationship
- Keyword (es)
- Actividad biológica Amida Apoptosis Cancerología Célula tumoral Melanoma maligno Fase G1 Relación estructura actividad Relación estructura función Relación estructura propiedad
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A01 Physicochemical properties. Structure-activity relationships
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04H Treatment. General aspects / 002B04H03 Combined treatment
- Discipline
- General pharmacology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16881285
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/ja042913p 
https://dx.doi.org/10.1021/ja042913p
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