Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system
- Author
- KUPERSHMIDT, S1 2 ; TAO YANG1 2 ; ANDERSON, M. E1 2 ; WESSELS, A3 ; NISWENDER, K. D4 ; MAGNUSON, M. A1 4 ; RODEN, D. M1 2
[1] Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn, United States
[2] Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tenn, United States
[3] Department of Cell Biology and Anatomy, Medical University of South Carolina, SC, United States
[4] Department of Molecular Physiology & Biophysics, Vanderbilt University School of Medicine, Nashville, Tenn, United States - Source
Circulation research. 1999, Vol 84, Num 2, pp 146-152 ; ref : 42 ref
- CODEN
- CIRUAL
- ISSN
- 0009-7330
- Scientific domain
- Cardiology, blood circulation, phlebology
- Publisher
- Lippincott, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal transgénique Coeur Courant ionique Délétion Développement Expression génique Gène Potassium ion QT long Recombinaison homologue Souris Système conduction Courant redressé Gène lacZ Gène minK Appareil circulatoire pathologie Appareil circulatoire Bloc cardiaque Cardiopathie Electrophysiologie Mammalia Rodentia Trouble conduction Trouble rythme cardiaque Vertebrata
- Keyword (en)
- Transgenic animal Heart Ionic current Deletion Development Gene expression Gene Potassium ion Prolonged QT interval Homologous recombination Mouse Conduction system Cardiovascular disease Circulatory system Heart block Heart disease Electrophysiology Mammalia Rodentia Conduction disorder Arrhythmia Vertebrata
- Keyword (es)
- Animal transgénico Corazón Corriente iónica Deleción Desarrollo Expresión genética Gen Potasio ion QT largo Recombinación homólogo Ratón Sistema conducción Aparato circulatorio patología Aparato circulatorio Bloque cardíaco Cardiopatía Electrofisiología Mammalia Rodentia Trastorno conducción Arritmia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A02 Cardiac dysrhythmias
- Discipline
- Cardiology. Circulatory system
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1691417
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1161/01.RES.84.2.146 
https://dx.doi.org/10.1161/01.RES.84.2.146
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