Synthesis of 2,4,6-trisubstituted pyrimidines as antimalarial agents
- Author
- AGARWAL, Anu1 ; SRIVASTAVA, Kumkum2 ; PURI, S. K2 ; CHAUHAN, Prem M. S1
[1] Division of Medicinal & Process Chemistry, Central Drug Research Institute, Lucknow 226001, India
[2] Diuision of Parasitology, Central Drug Research Institute, Lucknow 226001, India - Source
Bioorganic & medicinal chemistry. 2005, Vol 13, Num 15, pp 4645-4650, 6 p ; ref : 15 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Antimalarial Dihydrofolate reductase Pyrimidine
- Keyword (fr)
- Antipaludique Antiparasitaire Antiprotozoaire Benzène dérivé Cycle 5 chaînons Cycle 6 chaînons Hétérocycle azote In vitro Plasmodium falciparum Pyridine dérivé Pyrrolidine dérivé Relation structure activité Synthèse chimique Pyrimidine(4-aryl-2-pipéridino-6-[4-pyridyl]) Pyrimidine(4-aryl-6-[4-pyridyl]-2-pyrrolidino) Apicomplexa Protozoa
- Keyword (en)
- Antimalarial Parasiticide Antiprotozoal agent Benzene derivatives Five membered ring Six membered ring Nitrogen heterocycle In vitro Plasmodium falciparum Pyridine derivatives Pyrrolidine derivatives Structure activity relation Chemical synthesis Apicomplexa Protozoa
- Keyword (es)
- Antipalúdico Antiparasitario Antiprotozoario Benceno derivado Ciclo 5 eslabones Ciclo 6 eslabones Heterociclo nitrógeno In vitro Plasmodium falciparum Piridina derivado Relación estructura actividad Síntesis química Apicomplexa Protozoa
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16914867
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2005.04.061 
https://dx.doi.org/10.1016/j.bmc.2005.04.061
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