RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation
- Author
- SCHWÄBLE, Joachim; CHOUDHARY, Chunaram; MÜLLER-TIDOW, Carsten; SERVE, Hubert; THIEDE, Christian; TICKENBROCK, Lara; SARGIN, Bülent; STEUR, Claudia; REHAGE, Maike; RUDAT, Annika; BRANDTS, Christian; BERDEL, Wolfgang E
Department of Medicine, Hematology, and Oncology and the Interdisciplinary Clinical Research Center (IZKF), University of Münster, Münster, Germany
Department of Zoophysiology and Behaviour, Institute of Biology and Environmental Sciences, Carl-von-Ossietzky University, Oldenburg, Germany
Medizinische Klinik und Poliklinik I, Universitäts- klinikum Carl Gustav Carus der Technischen Universität, Dresden, Germany - Source
Blood. 2005, Vol 105, Num 5, pp 2107-2114, 8 p ; ref : 53 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- The Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aigu Carcinogenèse Cellule myéloïde Cytodifférenciation Gène Génétique Homme Leucémie myéloblastique Mutation Séquence répétée en tandem Transformation maligne Gène RGS2 Leucémogenèse Récepteur tyrosine kinase FLT3 Hémopathie maligne
- Keyword (en)
- Acute Carcinogenesis Myeloid cell Cell differentiation Gene Genetics Human Acute myelocytic leukemia Mutation Tandemly repeated sequence Malignant transformation Leukemogenesis Fms-like tyrosine kinase 3 Malignant hemopathy
- Keyword (es)
- Agudo Carcinogénesis Célula mieloide Diferenciación celular Gen Genética Hombre Leucemia mieloblástica Mutación Secuencia repetida en tándem Transformación maligna Hemopatía maligna
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16944125
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2004-03-0940 
https://dx.doi.org/10.1182/blood-2004-03-0940
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