Synthesis and immunosuppressive activity of new artemisinin derivatives. 1. [12(β or α)-dihydroartemisininoxy]phen(ox)yl aliphatic acids and esters
- Author
- YANG, Zhong-Shun1 ; ZHOU, Wen-Liang2 ; YING LI1 ; ZUO, Jian-Ping2 ; YI SUI1 ; WANG, Jun-Xia2 ; WU, Jin-Ming1 ; YU ZHOU2 ; YU ZHANG1 ; HE, Pei-Lan2 ; HAN, Ji-Ye1 ; WEI TANG2
[1] Department of Synthetic Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 201203, China
[2] First Department of Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 201203, China - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 14, pp 4608-4617, 10 p ; ref : 41 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Artémisinine Composé benzénique Cytotoxicité Endoperoxyde Erythrocyte Ester Hémolyse Immunodépresseur Immunomodulateur In vitro Relation structure activité Sesquiterpène Souris Synthèse chimique Terpénoïde Toxicité 3,12-Epoxypyrano[4,3-j]-1,2-benzodioxépine dérivé Benzènepropionique acide(4-hydroxy) ester méthyle Succinique acide ester Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Artemisinin Benzenic compound Cytotoxicity Endoperoxide Red blood cell Ester Hemolysis Immunosuppressive agent Immunomodulator In vitro Structure activity relation Sesquiterpenes Mouse Chemical synthesis Terpenoid Toxicity Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Artemisinina Compuesto bencénico Citotoxicidad Endoperóxido Eritrocito Ester Hemólisis Inmunodepresor Inmunomodulador In vitro Relación estructura actividad Sesquiterpeno Ratón Síntesis química Terpenoide Toxicidad Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02Q Immunomodulators
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16953112
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm048979c 
https://dx.doi.org/10.1021/jm048979c
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