Development of 5-iodo-2'-deoxyuridine milling process to reduce initial burst release from PLGA microparticles
- Author
- GEZE, A1 ; VENIER-JULIENNE, M. C1 ; MATHIEU, D2 ; FILMON, R3 ; PHAN-TAN-LUU, R2 ; BENOIT, J. P1
[1] UPRES EA 2169, Faculté de Pharmacie, 16, Boulevard Daviers, 49100 Angers, France
[2] Laboratoire de Méthodologie de la Recherche Expérimentale, Avenue Escadrille Normandie-Niemen, 13397 Marseille, France
[3] Service Commun de Microscopie Electronique. Faculté de Médecine, 1, rue Haute de Reculée, 49100 Angers, France - Source
International journal of pharmaceutics. 1999, Vol 178, Num 2, pp 257-268 ; ref : 17 ref
- CODEN
- IJPHDE
- ISSN
- 0378-5173
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Broyage Broyeur boulet Condition opératoire Désoxyribonucléoside Etude comparative Forme libération contrôlée Forme pharmaceutique Glycolique acide copolymère In vitro Iode composé Lactique acide copolymère Libération Microencapsulation Microsphère Procédé fabrication Surface réponse Séchage pulvérisation Technologie pharmaceutique Uridine
- Keyword (en)
- Grinding(comminution) Ball mill Operating conditions Deoxyribonucleoside Comparative study Controlled release form Dosage form Glycolic acid copolymer In vitro Iodine compounds Lactic acid copolymer Release Microencapsulation Microsphere Manufacturing process Response surface Spray drying Pharmaceutical technology Uridine
- Keyword (es)
- Molienda Molino bolas Condición operatoria Desoxirribonucleósido Estudio comparativo Forma liberación controlada Forma farmacéutica Glicolico acido copolimero In vitro Iodo compuesto Láctico ácido copolímero Liberación Microencapsulación Microsfera Procedimiento fabricación Superficie respuesta Secado pulverización Tecnología farmacéutica Uridina
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1697117
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0378-5173(98)00380-9 
https://dx.doi.org/10.1016/S0378-5173(98)00380-9
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