Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer
- Author
- HSU, Han-Shui1 2 ; WEN, Chiao-Kai3 ; TANG, Yen-An3 ; LIN, Ruo-Kai3 ; LI, Wing-Yin4 ; HSU, Wen-Hu1 ; WANG, Yi-Ching3
[1] Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taiwan, Province of China
[2] National Yang-Ming University Institute of Clinical Medicine, Taiwan, Province of China
[3] Department of Life Sciences, National Taiwan Normal University, Taipei, Taiwan, Province of China
[4] Department of Pathology, Taipei Veterans General Hospital, Taiwan, Province of China - Source
Clinical cancer research. 2005, Vol 11, Num 15, pp 5410-5416, 7 p ; ref : 29 ref
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Bronchopulmonaire Cancer du poumon Gène réparation Mécanisme action Méthylation Promoteur transcription Pronostic Gène hMLH1 Gène hMSH2 Appareil respiratoire pathologie Poumon pathologie
- Keyword (en)
- Bronchopulmonary Lung cancer Repair gene Mechanism of action Methylation Transcription promoter Prognosis Respiratory disease Lung disease
- Keyword (es)
- Broncopulmonar Cáncer del pulmón Gen reparación Mecanismo acción Metilación Promotor transcripción Pronóstico Aparato respiratorio patología Pulmón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pharmacological treatments Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16988741
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-05-0601 
https://dx.doi.org/10.1158/1078-0432.CCR-05-0601
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