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Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Aβ region of amyloid precursor protein

Author
POON, H. Fai1 ; FARR, Susan A2 3 ; BANKS, William A2 3 ; PIERCE, William M4 ; KLEIN, Jon B5 ; MORLEY, John E2 3 ; BUTTERFIELD, D. Allan1
[1] Department of Chemistry, Center of Membrane Sciences, and Sander-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, United States
[2] Geriatric Research Education and Clinical Center (GRECC), VA Medical Center, St. Louis, MO 63106, United States
[3] Department of Internal Medicine, Division of Geriatric Medicine, St. Louis University School of Medicine, St. Louis, MO 63110-0250, United States
[4] Department of Pharmacology, University of Louisville School of Medicine and VAMC, Louisville, KY 40292, United States
[5] Kidney Disease Program and Proteomics Core Laboratory, University of Louisville School of Medicine and VAMC, Louisville, KY 40292, United States
Source

Molecular brain research. 2005, Vol 138, Num 1, pp 8-16, 9 p ; ref : 87 ref

ISSN
0169-328X
Scientific domain
Biochemistry, molecular biology, biophysics; Genetics; Neurology; Physiology, morphology
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Alzheimer's disease Amyloid beta-peptide Amyloid precursor protein Antisense oligonucleotide Oxidative stress Proteomic identification SAMP8
Keyword (fr)
Animal Démence Alzheimer Oligonucléotide antisens Protéine amyloïde β Protéine précurseur amyloïde Protéomique Souris Stress oxydatif Sénescence Encéphale pathologie Maladie dégénérative Mammalia Rodentia Système nerveux central pathologie Système nerveux central Système nerveux pathologie Vertebrata
Keyword (en)
Animal Alzheimer disease Antisense oligonucleotide β Amyloid protein Amyloid precursor protein Proteomics Mouse Oxidative stress Senescence Cerebral disorder Degenerative disease Mammalia Rodentia Central nervous system disease Central nervous system Nervous system diseases Vertebrata
Keyword (es)
Animal Demencia Alzheimer Oligonucleótido antisentido Proteína amiloide β Proteína precursor amiloide Proteómica Ratón Estrés oxidativo Senescencia Encéfalo patología Enfermedad degenerativa Mammalia Rodentia Sistema nervosio central patología Sistema nervioso central Sistema nervioso patología Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Discipline
Neurology Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16992678

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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