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Biodistribution of 68Ga-labelled phosphodiester, phosphorothioate, and 2'-O-methyl phosphodiester oligonucleotides in normal rats

Author
LENDVAI, Gabor1 2 ; VELIKYAN, Irina1 3 ; BERGSTRÖM, Mats1 4 ; ESTRADA, Sergio1 ; LARYEA, Daniel1 ; VÄLILÄ, Maria5 6 ; SALOMÄKI, Satu5 6 ; LANGSTRÖM, Bengt1 3 ; ROIVAINEN, Anne1 5
[1] Uppsala Imanet, PO Box 967, 751 09 Uppsala, Sweden
[2] Department of Medical Sciences, Uppsala University Hospital, 751 85 Uppsala, Sweden
[3] Department of Organic Chemistry, Institute of Chemistry, Uppsala University, 751 24 Uppsala, Sweden
[4] Department of Pharmaceutical Biosciences, Uppsala Biomedical Centre, 751 24 Uppsala, Sweden
[5] Turku PET Centre, Turku University Hospital, 20521 Turku, Finland
[6] Department of Chemistry, University of Turku, 20014 Turku, Finland
Source

European journal of pharmaceutical sciences. 2005, Vol 26, Num 1, pp 26-38, 13 p ; ref : 1 p.3/4

ISSN
0928-0987
Scientific domain
Pharmacology drugs
Publisher
Elsevier, Shannon
Publication country
Ireland
Document type
Article
Language
English
Author keyword
68Ga Antisense oligonucleotides Distribution in vivo Hybridisation in solution Positron emission tomography Whole-body autoradiography
Keyword (fr)
Animal Autoradiographie Distribution In vivo Normal Oligonucléotide antisens Rat Solution Technologie pharmaceutique Thiophosphate organique Tomoscintigraphie Phosphorothioate dérivé Mammalia Pharmacocinétique Rodentia Vertebrata
Keyword (en)
Animal Autoradiography Distribution In vivo Normal Antisense oligonucleotide Rat Solution Pharmaceutical technology Organic thiophosphate Emission tomography Phosphorothioate derivatives Mammalia Pharmacokinetics Rodentia Vertebrata
Keyword (es)
Animal Autorradiografía Distribución In vivo Normal Oligonucleótido antisentido Rata Solución Tecnología farmacéutica Tiofosfato orgánico Tomocentelleografía Mammalia Farmacocinética Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17018168

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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