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The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation

Author
LIANG HUI1 ; PEI, Dong-Sheng1 ; ZHANG, Quan-Guang1 ; GUAN, Qiu-Hua1 ; ZHANG, Guang-Yi1
[1] Research Center for Biochemistry and Molecular Biology, Xuzhou Medical College, 84 West Huai-hai Road, Xuzhou 221002, Jiangsu, China
Source

Brain research. 2005, Vol 1052, Num 1, pp 1-9, 9 p ; ref : 31 ref

CODEN
BRREAP
ISSN
0006-8993
Scientific domain
Neurology; Physiology, morphology
Publisher
Elsevier, Amsterdam / Elsevier, London / Elsevier, New York, NY
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Aktl Bcl-2 Caspase-3 Cerebral ischemia/reperfusion (I/R) Hippocampus Insulin JNK1/2 LY294002 Phosphatidylinositol 3-kinase (PI3K) c-Jun
Keyword (fr)
1-Phosphatidylinositol 3-kinase Animal Encéphale Gène immédiat précoce Gène onc cellulaire Hippocampe Insuline Ischémie Lésion Neuroprotecteur Neuroprotection Protooncogène Rat Reperfusion Transduction signal Gène bcl2 c-Jun N-terminal kinase Appareil circulatoire pathologie Enzyme Hormone pancréatique Mammalia Rodentia Système nerveux central Transferases Vertebrata
Keyword (en)
1-Phosphatidylinositol 3-kinase Animal Encephalon Immediate early gene C-Onc gene Hippocampus Insulin Ischemia Lesion Neuroprotective agent Neuroprotection Protooncogene Rat Reperfusion Signal transduction c-Jun N-terminal kinase Cardiovascular disease Enzyme Pancreatic hormone Mammalia Rodentia Central nervous system Transferases Vertebrata
Keyword (es)
1-Phosphatidylinositol 3-kinase Animal Encéfalo Gen inmediato precoz Gen onc celular Hipocampo Insulina Isquemia Lesión Neuroprotector Neuroprotección Protooncogen Rata Reperfusión Transducción señal Aparato circulatorio patología Enzima Hormona pancreática Mammalia Rodentia Sistema nervioso central Transferases Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B10 Neuroprotective agent

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17C Vascular diseases and vascular malformations of the nervous system

Discipline
Neurology Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17019206

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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