Structural basis for the enantioselectivity of an epoxide ring opening reaction catalyzed by halo alcohol dehalogenase HheC
- Author
- DE JONG, René M1 ; TIESINGA, Jan J. W1 ; VILLA, Alessandra1 ; LIXIA TANG2 ; JANSSEN, Dick B2 ; DIJKSTRA, Bauke W1
[1] Department of Biophysical Chemistry and Biochemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, Netherlands
[2] Department of Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, Netherlands - Source
Journal of the American Chemical Society. 2005, Vol 127, Num 38, pp 13338-13343, 6 p ; ref : 38 ref
- CODEN
- JACSAT
- ISSN
- 0002-7863
- Scientific domain
- Biochemistry, molecular biology, biophysics; Chemistry; Organic chemistry; Atomic molecular physics
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Catalyse enzymatique Cycle 3 chaînons Décyclisation Enantiosélectivité Etude expérimentale Etude théorique Hétérocycle oxygène Modèle thermodynamique Méthode Hartree Fock Oxirane dérivé Paramètre thermodynamique Réaction catalytique Réaction nucléophile Régiosélectivité Haloalcohol dehalogenase
- Keyword (en)
- Enzymatic catalysis Three membered ring Ring cleavage Enantioselectivity Experimental study Theoretical study Oxygen heterocycle Thermodynamic model Hartree Fock method Oxirane derivatives Thermodynamic parameter Catalytic reaction Nucleophilic reaction Regioselectivity
- Keyword (es)
- Catálisis enzimática Ciclo 3 eslabones Desciclización Enantioselectividad Estudio experimental Estudio teórico Heterociclo oxígeno Modelo termodinámico Método Hartree Fock Oxirano derivado Parámetro termodinámico Reacción catalítica Reacción nucléofila Regioselectividad
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A03 Molecular biophysics / 002A03E Physical chemistry in biology / 002A03E01 Mechanisms. Catalysis. Electron transfer. Models
- Discipline
- Molecular biophysics
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17144558
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/ja0531733 
https://dx.doi.org/10.1021/ja0531733
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