Design, synthesis and in vitro and in vivo antitumor activities of novel β-carboline derivatives
- Author
- CAO, R1 ; CHEN, H1 ; PENG, W1 ; MA, Y1 ; HOU, X1 ; GUAN, H1 ; LIU, X1 ; XU, A1
[1] Department of Biochemistry and Center for Biopharmaceutical Research, College of Life Sciences, Sun Yat-sen (Zhongshan) University, 135 Xin Gang Xi Road, Guangzhou 510275, China - Source
European journal of medicinal chemistry. 2005, Vol 40, Num 10, pp 991-1001, 11 p ; ref : 32 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Acute toxicity Antitumor Cytotoxic SAR Synthesis β-Carboline
- Keyword (fr)
- Acylate Aigu Animal Anticancéreux Carbamate organique Carboline dérivé Cation organique Chimiothérapie Composé aromatique Composé tricyclique Cytotoxicité Ester Hétérocycle azote Iminium composé In vitro In vivo Relation structure activité Sarcome 180 Souris Synthèse chimique Système nerveux Toxicité Traitement Tumeur Lewis Voie intrapéritonéale Pyrido[3,4-b]indole dérivé Pyridoindole β-Carboline-3-carboxylique acide dérivé β-Carboline-3-méthanol dérivé β-Carbolinium composé Appareil respiratoire pathologie Mammalia Poumon pathologie Rodentia Tumeur maligne Vertebrata
- Keyword (en)
- Acylate Acute Animal Antineoplastic agent Organic carbamate Carboline derivatives Organic cation Chemotherapy Aromatic compound Tricyclic compound Cytotoxicity Ester Nitrogen heterocycle Iminium compounds In vitro In vivo Structure activity relation Sarcoma 180 Mouse Chemical synthesis Nervous system Toxicity Treatment Lewis lung carcinoma Intraperitoneal administration Respiratory disease Mammalia Lung disease Rodentia Malignant tumor Vertebrata
- Keyword (es)
- Acilato Agudo Animal Anticanceroso Carbamato orgánico Catión orgánico Quimioterapia Compuesto aromático Compuesto tricíclico Citotoxicidad Ester Heterociclo nitrógeno Iminio compuesto In vitro In vivo Relación estructura actividad Sarcoma 180 Ratón Síntesis química Sistema nervioso Toxicidad Tratamiento Tumor Lewis Vía intraperitoneal Aparato respiratorio patología Mammalia Pulmón patología Rodentia Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17169780
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2005.04.008 
https://dx.doi.org/10.1016/j.ejmech.2005.04.008
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