Variolin B and its derivate deoxy-variolin B : New marine natural compounds with cyclin-dependent kinase inhibitor activity
- Author
- SIMONE, Matteo1 ; ERBA, Eugenio1 ; DAMIA, Giovanna1 ; VIKHANSKAYA, Faina1 ; DI FRANCESCO, Angela M2 ; RICCARDI, Riccardo2 ; BAILLY, Christian3 ; CUEVAS, Carmen4 ; FERNANDEZ SOUSA-FARO, José Maria4 ; D'INCALCI, Maurizio1
[1] Department of Oncology, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, Milan, Italy
[2] Division of Pediatric Oncology, Catholic University A. Gemelli, Rome, Italy
[3] INSERM U-524 et Lahoratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, 59045 Lille, France
[4] Pharma Mar, SA, Colmenar Viejo, Madrid, Spain - Source
European journal of cancer (1990). 2005, Vol 41, Num 15, pp 2366-2377, 12 p ; ref : 20 ref
- ISSN
- 0959-8049
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis CDK inhibitors CDKs Marine natural compounds p53
- Keyword (fr)
- Activité biologique Apoptose Cancérologie Composé naturel Gène TP53 Gène suppresseur tumeur Milieu marin Mort cellulaire Pharmacologie Gène p53 Inhibiteur cyclin dependent kinase
- Keyword (en)
- Biological activity Apoptosis Cancerology Natural compound TP53 Gene Tumor suppressor gene Marine environment Cell death Pharmacology Cyclin dependent kinase inhibitor
- Keyword (es)
- Actividad biológica Apoptosis Cancerología Compuesto natural Gen TP53 Gen supresor tumor Medio marino Muerte celular Farmacología Inhibidor cyclin dependent kinase
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17186857
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejca.2005.05.015 
https://dx.doi.org/10.1016/j.ejca.2005.05.015
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