Low-level expression of proapoptotic bcl-2-lnteracting mediator in leukemic cells in patients with chronic myeloid leukemia : Role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds
- Author
- AICHBERGER, Karl J1 ; MAYERHOFER, Matthias1 ; SILLABER, Christian1 ; ESTERBAUER, Harald6 ; VALENT, Peter1 ; KRAUTH, Maria-Theresa1 ; VALES, Anja1 ; KONDO, Rudin1 ; DERDAK, Sophia2 ; PICKL, Winfried F2 ; SELZER, Edgar3 ; DEININGER, Michael4 ; DRUKER, Brian J5
[1] Department of Internal Medicine I, Division of Hematology and Hemostaseology the Center of Excellence in Clinical and Experimental Oncology, United States
[2] Institute of Immunology, Medical University of Vienna, Vienna, Austria
[3] Department of Radiation Therapy, Medical University of Vienna, Vienna, Austria
[4] Oregon Health and Science University Cancer Institute, Center for Hematological Malignancies, United States
[5] Howard Hughes Medical Institute, Portland, Oregon, United States
[6] Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria - Source
Cancer research (Baltimore). 2005, Vol 65, Num 20, pp 9436-9444, 9 p ; ref : 48 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Apoptose Chromosome C9 anormal Chromosome G22 anormal Chromosome Ph1 Chronique Expression génique Gène hybride Gène onc cellulaire Homme In vitro Leucémie myéloïde Médiateur Protein kinase Protooncogène Traitement Transduction signal Translocation chromosomique Gène abl Gène bcl2 Gène bcr Inhibiteur protéasome Protéine bcr-abl Voie de signalisation Aberration chromosomique Chromosome anormal Enzyme Hémopathie maligne Myéloprolifératif syndrome Transferases
- Keyword (en)
- Apoptosis Abnormal chromosome C9 Abnormal chromosome G22 Philadelphia chromosome Chronic Gene expression Hybrid gene C-Onc gene Human In vitro Chronic myelocytic leukemia Mediator Protein kinase Protooncogene Treatment Signal transduction Chromosome translocation Proteasome inhibitor Bcr-abl protein Signaling pathway Chromosomal aberration Abnormal chromosome Enzyme Malignant hemopathy Myeloproliferative syndrome Transferases
- Keyword (es)
- Apoptosis Cromosoma C9 anormal Cromosoma G22 anormal Cromosoma Ph1 Crónico Expresión genética Gen híbrido Gen onc celular Hombre In vitro Leucemia mieloidea Mediador Protein kinase Protooncogen Tratamiento Transducción señal Translocación cromosómica Aberración cromosómica Cromosoma anormal Enzima Hemopatía maligna Mieloproliferativo síndrome Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B23 Medical genetics / 002B23B Chromosome aberrations
- Discipline
- Blood diseases Medical genetics Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17205439
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-05-0972 
https://dx.doi.org/10.1158/0008-5472.CAN-05-0972
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