Influence of CYP2C9, 2C19 and 2D6 genetic polymorphisms on the steady-state plasma concentrations of the enantiomers of fluoxetine and norfluoxetine
- Author
- SCORDO, Maria G1 2 3 ; SPINA, Edoardo1 ; DAHL, Marja-Liisa3 ; GATTI, Giuliana4 ; PERUCCA, Emilio4
[1] Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Italy
[2] Division of Clinical Pharmacology, Karolinska Institutet, Huddinge University Hospital, Sweden
[3] Department of Medical Sciences, Clinical Pharmacology, University Hospital, Uppsala, Sweden
[4] Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Italy - Source
Basic & clinical pharmacology & toxicology (Print). 2005, Vol 97, Num 5, pp 296-301, 6 p ; ref : 35 ref
- ISSN
- 1742-7835
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Blackwell, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antidépresseur Cytochrome P450 Enantiomère Fluoxétine Génotype Isomère Isozyme Liquide biologique Pharmacocinétique Plasma sanguin Psychotrope Variabilité génétique Cytochrome P4502C9 Enzyme Inhibiteur recapture Inhibiteur sélectif recapture sérotonine Neurotransmetteur Sérotonine Tryptamine dérivé
- Keyword (en)
- Antidepressant agent Cytochrome P450 Enantiomer Fluoxetine Genotype Isomer Isozyme Biological fluid Pharmacokinetics Blood plasma Psychotropic Genetic variability Enzyme Reuptake inhibitor Selective serotonin reuptake inhibitor Neurotransmitter Serotonin Tryptamine derivatives
- Keyword (es)
- Antidepresor Citocromo P450 Enantiómero Fluoxetina Genotipo Isómero Isozima Líquido biológico Farmacocinética Plasma sanguíneo Psicotropo Variabilidad genética Enzima Inhibidor recaptura Inhibidor selectivo recaptura serotonin Neurotransmisor Serotonina
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17220359
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1742-7843.2005.pto_194.x 
https://dx.doi.org/10.1111/j.1742-7843.2005.pto_194.x
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