ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors
- Author
- RICH, Jeremy N1 2 3 ; SATHORNSUMETEE, Sith3 ; REARDON, David A3 7 ; RYAN, Anderson J8 ; WHEELER, Catherine9 ; DIMERY, Isaiah9 ; BIGNER, Darell D6 ; FRIEDMAN, Henry S3 7 ; KEIR, Stephen T3 ; KIERAN, Mark W4 5 ; LAFORME, Andrea4 5 ; KAIPAINEN, Arja5 ; MCLENDON, Roger E6 ; GRANER, Michael W6 ; AHMED RASHEED, B. K6 ; LING WANG6
[1] Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States
[2] Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, United States
[3] Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States
[4] Department of Pediatric Hematology-Oncology, Dana-Farber Cancer Institute, United States
[5] Surgical Research Laboratory, Children's Hospital, Department of Surgery, Harvard Medical School, Boston, Massachusetts, United States
[6] Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States
[7] Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, United States
[8] Cancer Discovery, AstraZeneca, Macclesfield, Cheshire, United Kingdom
[9] AstraZeneca, Wilmington, Delaware, United States - Source
Clinical cancer research. 2005, Vol 11, Num 22, pp 8145-8157, 13 p ; ref : 50 ref
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Facteur croissance endothélium vasculaire Inhibiteur enzyme Protein-tyrosine kinase Récepteur biologique Récepteur facteur croissance épiderme Récepteur facteur croissance Système nerveux Tumeur maligne Croissance tumorale Inhibiteur tyrosine kinase Enzyme Transferases
- Keyword (en)
- Vascular endothelium growth factor Enzyme inhibitor Protein-tyrosine kinase Biological receptor Epidermal growth factor receptor Growth factor receptor Nervous system Malignant tumor Tumor growth Tyrosine kinase inhibitor Enzyme Transferases
- Keyword (es)
- Factor crecimiento endotelio vascular Inhibidor enzima Protein-tyrosine kinase Receptor biológico Receptor factor crecimiento epidermi Receptor factor crecimiento Sistema nervioso Tumor maligno Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17316621
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-05-0319 
https://dx.doi.org/10.1158/1078-0432.CCR-05-0319
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