Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers
- Author
- LAMMERS, Twan1 2 ; KÜHNLEIN, Rainer1 ; PESCHKE, Peter1 ; KISSEL, Maria1 ; SUBR, Vladimir3 ; ETRYCH, Tomas3 ; POLA, Robert3 ; PECHAR, Michal3 ; ULBRICH, Karel3 ; STORM, Gert2 ; HUBER, Peter1
[1] Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
[2] Department of Pharmaceutical Technology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, P.O. Box 80082, 3508 TB Utrecht, Netherlands
[3] Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovsky Sq. 2, 162 06 Prague, Czech Republic - Source
Journal of controlled release. 2005, Vol 110, Num 1, pp 103-118, 16 p ; ref : 41 ref
- CODEN
- JCREEC
- ISSN
- 0168-3659
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Drug delivery EPR HPMA Polymer therapeutics Tumor targeting
- Keyword (fr)
- Ciblage Cible Distribution Médicament Méthacrylamide dérivé copolymère Polymère Technologie pharmaceutique Traitement Tumeur maligne Pharmacocinétique
- Keyword (en)
- Targeting Target Distribution Drug Methacrylamide derivative copolymer Polymer Pharmaceutical technology Treatment Malignant tumor Pharmacokinetics
- Keyword (es)
- Blancado Blanco Distribución Medicamento Metacrilamida derivado copolímero Polímero Tecnología farmacéutica Tratamiento Tumor maligno Farmacocinética
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17319882
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jconrel.2005.09.010 
https://dx.doi.org/10.1016/j.jconrel.2005.09.010
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