Developmental toxicity and toxicokinetics of two endothelin receptor antagonists in rats and rabbits
- Author
- TREINEN, K. A1 ; LOUDEN, C1 ; DENNIS, M. J2 ; WIER, P. J1
[1] Department of Safety Assessment, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406, United States
[2] Department ofDrug Metabolism and Pharmacokinetics, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406, United States - Source
Teratology (Philadelphia, PA). 1999, Vol 59, Num 1, pp 51-59 ; ref : 34 ref
- CODEN
- TJADAB
- ISSN
- 0040-3709
- Scientific domain
- Embryology, development; Genetics; Toxicology
- Publisher
- Wiley-Liss, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antagoniste Embryon Endothéline Foetus Indane dérivé Lapin Rat Récepteur biologique Récepteur peptidergique Toxicité Tératogène Voie intraveineuse Voie orale SB 209670 SB 217242 Hormone peptide Lagomorpha Mammalia Rodentia Vasoconstricteur Vertebrata
- Keyword (en)
- Animal Antagonist Embryo Endothelin Fetus Indan derivatives Rabbit Rat Biological receptor Peptidergic receptor Toxicity Teratogen Intravenous administration Oral administration Peptide hormone Lagomorpha Mammalia Rodentia Vasoconstrictor agent Vertebrata
- Keyword (es)
- Animal Antagonista Embrión Endothelina Feto Conejo Rata Receptor biológico Receptor peptidérgico Toxicidad Teratogeno Vía intravenosa Vía oral Hormona péptido Lagomorpha Mammalia Rodentia Vasoconstrictor Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U10 Miscellaneous (drug allergy, mutagens, teratogens...)
- Discipline
- Drugs toxicity and drug intoxications Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1734923
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/(SICI)1096-9926(199901)59:1<51::AID-TERA10>3.0.CO;2-I 
https://dx.doi.org/10.1002/(SICI)1096-9926(199901)59:1<51::AID-TERA10>3.0.CO;2-I
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