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Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease

Author
VAN RAAMSDONK, Jeremy M1 2 ; MURPHY, Zoe1 2 ; SLOW, Elizabeth J1 2 ; LEAVITT, Blair R1 2 ; HAYDEN, Michael R1 2
[1] Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada
[2] Centre for Molecular Medicine and Therapeutics, British Columbia Research Institute for Children's and Women's Health, Vancouver, BC V5Z 4H4, Canada
Source

Human molecular genetics (Print). 2005, Vol 14, Num 24, pp 3823-3835, 13 p ; ref : 61 ref

ISSN
0964-6906
Scientific domain
Genetics
Publisher
Oxford University Press, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Chorée Huntington Dégénérescence Génétique Huntingtine Localisation Modèle animal Mutation Souris Encéphale pathologie Extrapyramidal syndrome Maladie dégénérative Maladie héréditaire Mammalia Rodentia Système nerveux central pathologie Système nerveux pathologie Vertebrata
Keyword (en)
Huntington disease Degeneration Genetics Huntingtin Localization Animal model Mutation Mouse Cerebral disorder Extrapyramidal syndrome Degenerative disease Genetic disease Mammalia Rodentia Central nervous system disease Nervous system diseases Vertebrata
Keyword (es)
Corea Huntington Degeneración Genética Huntingtina Localización Modelo animal Mutación Ratón Encéfalo patología Extrapiramidal síndrome Enfermedad degenerativa Enfermedad hereditaria Mammalia Rodentia Sistema nervosio central patología Sistema nervioso patología Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Discipline
Eukaryotes genetics. Biological and molecular evolution Molecular and cell biology Neurology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17450575

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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