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Sensitive quantification of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry

Author
HOFMANN, Ute1 ; SCHWAB, Matthias1 ; TREIBER, Gerd2 ; KLOTZ, Ulrich1
[1] Dr. Margarete Fischer -Bosch -Institute of Clinical Pharmacology, Auerbachstrafie 112, 70376 Stuttgart, Germany
[2] Department of Gastroenterology and Hepatology, University Hospital Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany
Source

Journal of chromatography. B. 2006, Vol 831, Num 1-2, pp 85-90, 6 p ; ref : 13 ref

ISSN
1570-0232
Scientific domain
Medical laboratory techniques; Pharmacology drugs
Publisher
Elsevier Science, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
LC-MS Metabolites Omeprazole
Keyword (fr)
Antisécrétoire Antiulcéreux Chromatographie phase liquide Homme Liquide biologique Métabolite Méthode étude Oméprazole Plasma sanguin Spectrométrie masse Benzimidazole dérivé Enzyme H+/K+-exchanging ATPase Hydrolases Inhibiteur enzyme Inhibiteur pompe proton
Keyword (en)
Antisecretory agent Antiulcer agent Liquid chromatography Human Biological fluid Metabolite Investigation method Omeprazole Blood plasma Mass spectrometry Benzimidazole derivatives Enzyme H+/K+-exchanging ATPase Hydrolases Enzyme inhibitor Proton pump inhibitor
Keyword (es)
Antisecretorio Antiulceroso Cromatografía fase líquida Hombre Líquido biológico Metabolito Método estudio Omeprazol Plasma sanguíneo Espectrometría masa Benzimidazol derivado Enzima H+/K+-exchanging ATPase Hydrolases Inhibidor enzima Inhibidor bomba protón
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis

Discipline
Analytical, structural and metabolic biochemistry General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17461150

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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