Inhibitors of Rho-kinase modulate amyloid-β (Aβ) secretion but lack selectivity for Aβ42
- Author
- LEUCHTENBERGER, Stefanie1 ; KUMMER, Markus P2 ; KOO, Edward H2 ; WEGGEN, Sascha1 ; KUKAR, Thomas3 ; CZIRR, Eva1 ; TEUSCH, Nicole4 ; SAGI, Sarah A2 ; BERDEAUX, Rebecca5 ; PIETRZIK, Claus U6 ; LADD, Thomas B3 ; GOLDE, Todd E3
[1] Emmy Noether Research Group, Institute of Physiological Chemistry and Pathobiochemistry, Johannes Gutenberg University Mainz, Mainz, Germany
[2] Department of Neurosciences, University of California, San Diego, La Jolla, California, United States
[3] Department of Neuroscience and Pharmacology, Mayo Clinic Jacksonville, Jacksonville, Florida, United States
[4] Neuroscience Discovery Research, Abbott GmbH & Co. KG, Ludwigshafen, Germany
[5] Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, La Jolla, California, United States
[6] Molecular Neurodegeneration Group, Institute of Physiological Chemistry and Pathobiochemistry, Johannes Gutenberg University Mainz, Mainz, Germany - Source
Journal of neurochemistry. 2006, Vol 96, Num 2, pp 355-365, 11 p ; ref : 1 p.1/4
- CODEN
- JONRA9
- ISSN
- 0022-3042
- Scientific domain
- Cell biology, histology; Neurology; Physiology, morphology
- Publisher
- Blackwell, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Rho kinase amyloid precursor protein amyloid-p peptide non-steroidal anti-inflammatory drugs presenilin γ-secretase
- Keyword (fr)
- In vitro Lignée cellulaire Modulation Médicament Peptide Protéine précurseur amyloïde Sécrétion Sélectivité dGTPase Rho kinase Enzyme Esterases Hydrolases Triphosphoric monoester hydrolases
- Keyword (en)
- In vitro Cell line Modulation Drug Peptides Amyloid precursor protein Secretion Selectivity dGTPase Rho kinase Enzyme Esterases Hydrolases Triphosphoric monoester hydrolases
- Keyword (es)
- In vitro Línea celular Modulación Medicamento Péptido Proteína precursor amiloide Secreción Selectividad dGTPase Rho kinase Enzima Esterases Hydrolases Triphosphoric monoester hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H07 Secretion. Exocytosis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Molecular and cell biology Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17476916
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1471-4159.2005.03553.x 
https://dx.doi.org/10.1111/j.1471-4159.2005.03553.x
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