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O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

Author
HERMISSON, Mirjam1 ; KLUMPP, Andrea1 ; WICK, Wolfgang1 ; WISCHHUSEN, Jörg1 ; NAGEL, Georg2 ; ROOS, Wynand2 ; KAINA, Bernd2 ; WELLER, Michael1
[1] Laboratory of Molecular Neuro-Oncology, Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, School of Medicine, Tübingen, Germany
[2] Institute of Toxicology, University of Mainz, Mainz, Germany
Source

Journal of neurochemistry. 2006, Vol 96, Num 3, pp 766-776, 11 p ; ref : 1 p.1/2

CODEN
JONRA9
ISSN
0022-3042
Scientific domain
Cell biology, histology; Neurology; Physiology, morphology
Publisher
Blackwell, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
BCL-XL O6-methylguanine DNA methyltransferase glioblastoma p53 temozolomide
Keyword (fr)
Aigu Chimiothérapie Glioblastome Gliome malin Homme Lignée cellulaire Methyltransferases Prolongé Récidivant Réparation Résistance Sensibilité Survie Traitement Tumeur maligne Protéine Bcl-XL Enzyme Système nerveux central pathologie Système nerveux pathologie Transferases
Keyword (en)
Acute Chemotherapy Glioblastoma Malignant glioma Human Cell line Methyltransferases Prolonged Recurrent Repair Resistance Sensitivity Survival Treatment Malignant tumor Bcl-XL protein Enzyme Central nervous system disease Nervous system diseases Transferases
Keyword (es)
Agudo Quimioterapia Glioblastoma Glioma maligno Hombre Línea celular Methyltransferases Prolongado Recidivante Reparación Resistencia Sensibilidad Sobrevivencia Tratamiento Tumor maligno Enzima Sistema nervosio central patología Sistema nervioso patología Transferases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25C Isolated neuron and nerve. Neuroglia

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses

Discipline
Neurology Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17477384

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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