Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase b/akt-mediated potentiation of angiogenesis and inhibition of apoptosis
- Author
- GADAU, S1 ; EMANUELI, C2 3 ; MADEDDU, P1 6 ; VAN LINTHOUT, S1 ; GRAIANI, G2 ; TODARO, M4 ; MELONI, M2 ; CAMPESI, I2 ; INVERNICI, G5 ; SPILLMANN, F1 ; WARD, K1
[1] Experimental Medicine and Gene Therapy, National Institute of Biostructures and Biosystems (INBB), Osilo, Italy
[2] Molecular and Cellular Medicine, National Institute of Biostructures and Biosystems (INBB), Alghero, Italy
[3] Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, Bristol BS2 8HW, United Kingdom
[4] Cellular and Molecular Pathophysiology Laboratory, University of Palermo, Palermo, Italy
[5] Besta Neurological Institute, Milan, Italy
[6] Multimedica Research Institute, Milan, Italy - Source
Diabetologia (Berlin). 2006, Vol 49, Num 2, pp 405-420, 16 p ; ref : 52 ref
- ISSN
- 0012-186X
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- AGEs Advanced glycation end-products Angiogenesis Apoptosis Benfotiamine Caspase Diabetes Endothelial progenitor cells Ischaemia Vitamin B1
- Keyword (fr)
- Age Akt protein kinase Angiogenèse Animal Apoptose Caspase Cellule endothéliale Cellule précurseur Cysteine endopeptidases Diabète Inhibition Ischémie Produit réaction Souris Vitamine Appareil circulatoire pathologie Endocrinopathie Enzyme Hydrolases Mammalia Micronutriment Mort cellulaire Peptidases Rodentia Vertebrata
- Keyword (en)
- Age Akt protein kinase Angiogenesis Animal Apoptosis Caspase Endothelial cell Precursor cell Cysteine endopeptidases Diabetes mellitus Inhibition Ischemia Reaction product Mouse Vitamin Cardiovascular disease Endocrinopathy Enzyme Hydrolases Mammalia Micronutrient Cell death Peptidases Rodentia Vertebrata
- Keyword (es)
- Edad Akt protein kinase Angiogénesis Animal Apoptosis Caspase Célula endotelial Célula precursor Cysteine endopeptidases Diabetes Inhibición Isquemia Producto reacción Ratón Vitamina Aparato circulatorio patología Endocrinopatía Enzima Hydrolases Mammalia Micronutriente Muerte celular Peptidases Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Discipline
- Endocrinopathies
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17491652
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00125-005-0103-5 
https://dx.doi.org/10.1007/s00125-005-0103-5
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