Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma
- Author
- REARDON, David A1 2 ; QUINN, Jennifer A1 3 ; PROVENZALE, James M6 ; SAMPSON, John H1 ; SMITH, Robert P7 ; SWAISLAND, Alan J7 ; OCHS, Judith S7 ; LYONS, Peggy1 ; TOURT-UHLIG, Sandy1 ; BIGNER, Darell D5 ; FRIEDMAN, Henry S1 2 ; RICH, Jeremy N1 3 ; VREDENBURGH, James J1 3 ; GURURANGAN, Sridharan1 2 ; FRIEDMAN, Allan H1 ; DESJARDINS, Annick3 ; SATHORNSUMETEE, Sith3 ; HERNDON, James E4 ; DOWELL, Jeannette M4 ; MCLENDON, Roger E5
[1] Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States
[2] Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, United States
[3] Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States
[4] Department of Cancer Center Biostatistics, Duke University Medical Center, Durham, North Carolina, United States
[5] Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States
[6] Department of Radiology, Duke University Medical Center, Durham, North Carolina, United States
[7] AstraZeneca Pharmaceuticals, Wilmington, Delaware, United States - Source
Clinical cancer research. 2006, Vol 12, Num 3, pp 860-868, 9 p ; 1 ; ref : 46 ref
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adulte Anticancéreux Essai clinique phase I Gliome malin Géfitinib Récidive Sirolimus Inhibiteur synthèse protéique Inhibiteur tyrosine kinase Enzyme Homme Inhibiteur enzyme Lactone Macrocycle Macrolide Protein-tyrosine kinase Quinazoline dérivé Récepteur facteur croissance épiderme Système nerveux central pathologie Système nerveux pathologie Transferases Tumeur maligne
- Keyword (en)
- Adult Antineoplastic agent Phase I trial Malignant glioma Gefitinib Relapse Sirolimus Enzyme Human Enzyme inhibitor Lactone Macrocycle Macrolide Protein-tyrosine kinase Quinazoline derivatives Epidermal growth factor receptor Central nervous system disease Nervous system diseases Transferases Malignant tumor
- Keyword (es)
- Adulto Anticanceroso Ensayo clínico fase I Glioma maligno Gefitinib Recaida Sirolimús Enzima Hombre Inhibidor enzima Lactona Macrociclo Macrólido Protein-tyrosine kinase Receptor factor crecimiento epidermi Sistema nervosio central patología Sistema nervioso patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses
- Discipline
- Neurology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17515760
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-05-2215 
https://dx.doi.org/10.1158/1078-0432.CCR-05-2215
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