Molecular mechanism of 7TM receptor activation : A global toggle switch model
- Author
- SCHWARTZ, Thue W; FRIMURER, Thomas M; HOIST, Birgitte; ROSENKILDE, Mette M; ELLING, Christian E
[1] Laboratory for Molecular Pharmacology, The Panum Institute, University of Copenhagen, Denmark
[2] 7TM Pharma A/S, Hørsholm, Denmark - Source
Annual review of pharmacology and toxicology. 2006, Vol 46, pp 481-519, 39 p ; ref : 185 ref
- ISSN
- 0362-1642
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Annual Reviews, Palo Alto, CA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- G protein-coupled receptors agonist binding allosteric mechanism antagonism rhodopsin-like receptors
- Keyword (fr)
- Agoniste Antagonisme Article synthèse Mécanisme action Protéine G Rhodopsine Récepteur biologique Structure hélice Structure moléculaire Récepteur couplé protéine G Récepteur transmembranaire
- Keyword (en)
- Agonist Antagonism Review Mechanism of action G protein Rhodopsin Biological receptor Helical structure Molecular structure G protein coupled receptor
- Keyword (es)
- Agonista Antagonismo Artículo síntesis Mecanismo acción Proteína G Rodopsina Receptor biológico Estructura helicoidal Estructura molecular Receptor acoplado proteína G
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02D Proteins / 002A02D10 Miscellaneous
- Discipline
- Analytical, structural and metabolic biochemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17535911
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1146/annurev.pharmtox.46.120604.141218 
https://dx.doi.org/10.1146/annurev.pharmtox.46.120604.141218
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