Synthesis of chalcone analogues with increased antileishmanial activity
- Author
- BOECK, Paula1 ; BANDEIRA FALCAO, Camila Alves2 ; CESAR LEAL, Paulo1 ; AUGUSTO YUNES, Rosendo1 ; FILHO, Valdir Cechinel3 ; TORRES-SANTOS, Eduardo Caio2 ; ROSSI-BERGMANN, Bartira2
[1] Universidade Federal de Santa Catarina, Departamento de Quîmica, Campus Trindade, CEP 88.040-90, Florianópolis, SC, Brazil
[2] Universidade Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho, Ilha do Fundão, CEP 21.949-900 Rio de Janeiro, RJ, Brazil
[3] Núcleo de Imestigações Quimico -Farmacêuticas (NIQFAICCS), Universidade do Vale do Itajaí, CEP 88.303-202 Itajaí, SC, Brazil - Source
Bioorganic & medicinal chemistry. 2006, Vol 14, Num 5, pp 1538-1545, 8 p ; ref : 23 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Chalcone Cutaneous leishmaniasis Leishmania Xanthoxyline
- Keyword (fr)
- Amastigote Animal Antiparasitaire Antiprotozoaire Benzène dérivé Chimiothérapie Composé nitro Cétonephénols Flavonoïde Halogénophénols In vitro In vivo Intracellulaire Leishmania amazonensis Leishmaniose Promastigote Relation structure activité Souris Synthèse chimique Sélectivité Traitement Chalcone dérivé Brome Composé organique Fluor Composé organique Infection Kinetoplastida Mammalia Parasitose Protozoa Protozoose Rodentia Vertebrata
- Keyword (en)
- Amastigote Animal Parasiticide Antiprotozoal agent Benzene derivatives Chemotherapy Nitro compound Ketophenols Flavonoid Halophenols In vitro In vivo Intracellular Leishmania amazonensis Leishmaniasis Promastigote Structure activity relation Mouse Chemical synthesis Selectivity Treatment Bromine Organic compounds Fluorine Organic compounds Infection Kinetoplastida Mammalia Parasitosis Protozoa Protozoal disease Rodentia Vertebrata
- Keyword (es)
- Amastigota Animal Antiparasitario Antiprotozoario Benceno derivado Quimioterapia Compuesto nitro Cetofenoles Flavonoide Halofenoles In vitro In vivo Intracelular Leishmania amazonensis Leishmaniosis Promastigota Relación estructura actividad Ratón Síntesis química Selectividad Tratamiento Bromo Compuesto orgánico Fluor Compuesto orgánico Infección Kinetoplastida Mammalia Parasitosis Protozoa Protozoosis Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17555159
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2005.10.005 
https://dx.doi.org/10.1016/j.bmc.2005.10.005
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