Intermolecular interactions in the crystal structures of potential HIV-1 integrase inhibitors
- Author
- MAJERZ-MANIECKA, Katarzyna1 ; MUSIOL, Robert2 ; NITEK, Wojciech1 ; OLEKSYN, Barbara J1 ; MOUSCADET, Jean-Francois3 ; LE BRET, Marc3 ; POLANSKI, Jaroslaw2
[1] Faculty of Chemistry, Jagiellonian University, ul. R. Ingardena 3, 30-060 Kraków, Poland
[2] Institute of Chemistry, University of Silesia, ul. Szkolna 9, CNRS UMR 8532, 40-007 Katowice, Poland
[3] LBPA, Ecole Normale Supérieure de Cachan, 94235 Cachan, France - Source
Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 4, pp 1005-1009, 5 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Crystal structure HIV-1 integrase inhibitor Quinoline
- Keyword (fr)
- Activité biologique Antiviral Chlore composé organique Composé nitro Conformation Diffraction RX Etude théorique In vitro Inhibiteur enzyme Interaction moléculaire Liaison hydrogène intramoléculaire Méthode semiempirique Nucleotidyltransferases Oxime Produit synthétique Quinoléine dérivé Structure cristalline Virus HIV1 Inhibiteur integrase Integrase Quinoléin-8-ol(2-[2,5-dichloro-4-nitro-anilino méthoxy méthyl]) Enzyme Lentivirus Retroviridae Transferases Virus immunodéficience humaine Virus
- Keyword (en)
- Biological activity Antiviral Organic chlorine compounds Nitro compound Conformation X ray diffraction Theoretical study In vitro Enzyme inhibitor Molecular interaction Intramolecular hydrogen bond Semiempirical method Nucleotidyltransferases Oxime Synthetic product Quinoline derivatives Crystalline structure HIV-1 virus Enzyme Lentivirus Retroviridae Transferases Human immunodeficiency virus Virus
- Keyword (es)
- Actividad biológica Antiviral Compuesto nitro Conformación Difracción RX Estudio teórico In vitro Inhibidor enzima Interacción molecular Enlace hidrógeno intramolecular Método semiempírico Nucleotidyltransferases Oxima Producto sintético Quinolina derivado Estructura cristalina HIV-1 virus Enzima Lentivirus Retroviridae Transferases Human immunodeficiency virus Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17557090
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2005.10.083 
https://dx.doi.org/10.1016/j.bmcl.2005.10.083
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